Βιογραφικό

Δρ. Λίνα Ευγενή

Δρ. Λίνα Ευγενή

Διευθύντρια – Βιολόγος Αναπαραγωγής, M.Phil Πανεπιστημίου Nottingham U.K., Διδάκτωρ ΔΠΘ

Η Διευθύντρια της Τράπεζας Κρυοσυντήρησης “ΚΡΥΟΓΟΝΙΑ”, Δρ Λίνα Α. Ευγενή, είναι Βιολόγος Αναπαραγωγής, ειδικευμένη στην ανάλυση και κρυοσυντήρηση σπέρματος και ορχικού ιστού, με πολυετή εμπειρία στην αξιολόγηση και διατήρηση της ανδρικής γονιμότητας.

Αποφοίτησε από το Τμήμα Βιολογίας της Σχολής Θετικών Επιστημών του Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών, στο οποίο είχε εισαχθεί πρώτη μεταξύ των υποψηφίων του έτους της. Στη συνέχεια, φοίτησε με υποτροφία στην Ιατρική Σχολή του University of Nottingham της Μεγάλης Βρετανίας, από την οποία απέκτησε μεταπτυχιακό τίτλο Master δι ερεύνης (M.Phil), με επιβλέποντα καθηγητή τον Prof. Simon Fishel, πρωτοπόρο της εξωσωματικής γονιμοποίησης και δημιουργό της μεθόδου SUZI (Sub zonal Insemination). Κατά τη διάρκεια των μεταπτυχιακών της σπουδών, εκπαιδεύτηκε στο ανδρολογικό εργαστήριο του κορυφαίου νοσοκομείου της Αγγλίας Queen’s Medical Centre, στις τεχνικές αξιολόγησης των βασικών και λειτουργικών παραμέτρων, καθώς και στις εφαρμογές της κρυοσυντήρησης σπέρματος και ορχικού ιστού.

Είναι Διδάκτωρ του Τμήματος Ιατρικής του Δημοκριτείου Πανεπιστημίου Θράκης και επιστημονική συνεργάτιδα του Μεταπτυχιακού Τμήματος Σπουδών με τίτλο ‘Ανθρώπινη Αναπαραγωγή’, στο οποίο συμμετέχει από την έναρξη της λειτουργίας του, με διαλέξεις και πρακτικές εργαστηριακές εκπαιδεύσεις.

Πιστοποιήσεις

Εργάζεται από το 1995 στον χώρο της Εργαστηριακής Σπερματολογίας, ως ιδρυτικό στέλεχος και διευθύντρια του ανδρολογικού εργαστηρίου της μεγαλύτερης και πρώτης πιστοποιημένης τράπεζας σπέρματος της Ελλάδας. Είναι υπεύθυνη του συστήματος διασφάλισης ποιότητας, σε συνεργασία με το πρόγραμμα Εξωτερικού Ποιοτικού Ελέγχου της ESHRE (European Society of Human Reproduction and Embryology).

Κατέχει πιστοποίηση από την Ευρωπαϊκή Εταιρεία Ανθρώπινης Αναπαραγωγής και Εμβρυολογίας (ESHRE) ως εκπαιδεύτρια για τη βασική ανάλυση σπέρματος. Στο πλαίσιο της επιστημονικής της δράσης, συμμετέχει ενεργά στη διενέργεια εκπαιδευτικών σεμιναρίων, ως ομιλήτρια σε συνέδρια και ως συγγραφέας επιστημονικών άρθρων και συγγραμμάτων, εκ των οποίων το πρώτο της βιβλίο εκδόθηκε το 2010 με τίτλο ‘Η ΛΕΙΤΟΥΡΓΙΑ ΤΟΥ ΑΝΔΡΙΚΟΥ ΣΠΕΡΜΑΤΟΣ’.

Επιστημονικές Μελέτες​

Μέρος των ερευνητικών της μελετών περιλαμβάνεται στο 6ο Εγχειρίδιο του Παγκόσμιου Οργανισμού Υγείας για την Ανάλυση και Επεξεργασία του ανδρικού σπέρματος (6th Edition of the WHO laboratory manual for the examination and processing of human semen) (2021), αποτελώντας την πρώτη Ελληνική συμμετοχή στα νέα παγκόσμια όρια αναφοράς για τις βασικές σπερματολογικές παραμέτρους.

Μέσω προηγμένων εφαρμογών στην εργαστηριακή διαχείριση του ανδρικού σπέρματος, παρέχει εκσυγχρονισμένες και εξατομικευμένες υπηρεσίες σε ζευγάρια με ανδρικό παράγοντα υπογονιμότητας, αλλά και γυναίκες χωρίς σύντροφο, που επιθυμούν να βιώσουν τη χαρά της μητρότητας.

  • Mangoli V, Evgeni E, Wyns C. Sperm cryopreservation protocol for micro-TESE-retrieved sperm. Asian J Androl. 2024 Sep 10. doi: 10.4103/aja202466. Epub ahead of print. PMID: 39254400.

  • Potiris, A.; Voitse, A.; Mavrogianni, D.; Machairiotis, N.; Drakaki, E.; Papamentzelopoulou,M.; Karampitsakos, T.; Zikopoulos, A.; Evgeni, E.; Drakakis, P.; et al. Association of GSTM1 Polymorphism and Redox Potential with Idiopathic Male Infertility. J. Clin. Med. 2023, 12,6775. https://doi.org/10.3390/jcm12216775

  • Gupta S, Sharma R, Agarwal A, Boitrelle F, Finelli R, Evgeni E, et al. Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices. World J Men’s Health. 2022 Jul;40(3):380-398. doi: 10.5534/wjmh.210164. Epub 2022 Jan 1. PMID: 35021297; PMCID: PMC9253805.

  • Björndahl L, Barratt CLR, Mortimer D, Agarwal A, Aitken RJ, Evgeni EA, et al. Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology. Hum Reprod. 2022 Oct 31;37(11):2497–2502. doi: 10.1093/humrep/deac189. PMID: 36112046; PMCID: PMC9627864.

  • Marić T, Wójcik I, Katušić Bojanac A, Matijević A, Ceppi M, Bruzzone M, Evgeni E, Petrović T, Trbojević- Akmačić I, Lauc G, Ježek D, Fučić Seminal plasma N-glycome as a new biomarker of environmental exposure associated with semen quality. Reprod Toxicol. 2022 Oct;113:96-102. doi: 10.1016/j.reprotox.2022.08.005. Epub 2022 Aug 10. PMID: 35961531.

  • “Hot Topics in Reproductive Biology – The State of the Art of ART for Reproductive Professionals” – Sperm Functional Tests: Usefulness in assessing male infertility and ART outcomes. Panminerva Med. 2023 Jun;65(2):135-147. doi: 10.23736/S0031-0808.23.04836-X. Epub 2023 Apr 27.

  • Symeonidis EN, Evgeni E, Palapelas V et al. Redox Balance in Male Infertility: Excellence through Moderation “Μέτρον ἄριστον” Antioxidants 2021 DOI: 10.3390/antiox10101534

  • Maric T, Bojanac AK, Matijevic A, Ceppi M, Bruzzone M, Evgeni E et al. Seminal Plasma Protein N-Glycan Peaks Are Potential Predictors of Semen Pathology and Sperm Chromatin Maturity in Men. Life 2021 11(9):989 DOI: 10.3390/life11090989

  • Maric T, Fucic A, Ceppi M, Bruzzone M, Evgeni E, Petrovic T, Trbojevic-Akmacic I, Lauc G, Jezek D. Integrated approach to the evaluation of male infertility: genome damage, sperm chromatin maturity and glycan composition. CERM Poster presentation 2021

  • Evgeni E, Lymberopoulos G, Gazouli M, Asimakopoulos B. Conventional semen parameters and DNA fragmentation in relation to fertility status in a Greek population. Eur J Obstet Gynecol Reprod Biol. 2015 Feb 26;188:17-23.*

  • Evgeni E, Lymberopoulos G, Touloupidis S, Asimakopoulos B. Sperm nuclear DNA fragmentation and its association with semen quality in Greek men. Andrologia 2015, xx, 1-9.*

  • Evgeni E, Charalabopoulos K, Asimakopoulos B. Human Sperm DNA Fragmentation and its Correlation with Conventional Semen Parameters. J Reprod Infertil 2014, 15(1): 2-14.

  • Evgeni Ε, Kouri Α. Sperm cryopreservation: laboratory techniques. ANIR 2013, 13:1, 8-13 [GR]
  • Evgeni A. and Lymberopoulos G.I. “New W.H.O. reference values for the conventional semen parameters”. Subjects of Obstetrics and Gynaecology 2010 2, 80-84. [GR]

  • Evgeni E, Ilias I, Alexiou M, Koukkou E, Venaki E, Lymberopoulos G and Nicopoulou SC. Evaluation of the initial semen analysis in Greek infertile couples. Int J Androl 2010, 33 (suppl 1): 4-20. O5-49

  • Evgeni E, Lymberopoulos G and Asvestis C. “Genetic and clinical aspects of azoospermia and severe oligozoospermia in Greek infertile men” Int J Androl 2010, 33 (suppl 1): 4-20. P35.

  • Evgeni E.A. and Lymberopoulos G.I. “The role of oxidative stress in semen quality. Pathophysiology – Diagnostic evaluation” ANIR 2010 12(3), 45-62. [GR]

  • Lymberopoulos G.I. and Evgeni L. “Sperm DNA Fragmentation” ANIR 2007 9(2), 103-115. [GR]

  • Lymberopoulos G.I. and Evgeni E.A. “Cancer and Fertility: Post therapy perspectives – Semen cryopreservation” ANIR 2002 1(4), 15-23. [GR]

*cited in the 6th WHO laboratory manual for the examination and processing of human semen (2021).

  • Translation of the 6th Edition of the WHO Manual for the Examination and Processing of Human Semen (WHO 2021) into Greek (coordinated by Prof. Goulis). 2024

  • Book Chapter: ‘Genetic and Genomic Tests of Infertile Men’ Elsevier: ‘Male Infertility’. 2022

  • Book Chapter: ‘Sperm Motility’ Springer: ‘Human Semen Analysis: From the WHO Manual to the Clinical Management of Infertile Men’. 2022

  • Chapter entitled «Sperm Banking» for the Seminar on the subject of “Reproductive Science in Biology & Medicine“, scientific advisor Prof. Georgiou Ioannis – University of Ioannina, 2018

  • Doctoral thesis titled: Evaluation of sperm nuclear DNA integrity in infertile men: correlation with conventional seminal parameters. Alexandroupolis, 2015

  • Book: Evgeni L and Lymberopoulos G. ‘The function of Human Semen: Diagnostic evaluation of disorders – Therapeutic management’ Beta Med Arts (2010) BOOK xvi+336 [GR] ISBN: 978-960-452-100-5

  • Master’s thesis titled: “A Comparison of two Sperm Cryopreservation Media in relation to Conventional Semen Parameters, Sperm Function Tests and Bioactivity” (Nottingham, 1995 – 1997).

  • Sperm Cryopreservation: Opportunities for Ovarian Fertility Preservation and Gamete Donation, 8th Panhellenic Conference on Thermal Medicine & Assisted Reproduction – Athens 2024

  • Poster: P149 “Age as a factor of male infertility – Alterations in the levels of sperm DNA fragmentationin the Greek population” . T Loumakos, G Kanakis, D Stathopoulos, P Kotrotsos, E Evgeni, 13th European Academy of Andrology Congress – Stockholm 2024

  • Consequences of Irrational Use of Antioxidants, Andrology Workshop – Cutting-Edge Topics in Andrology – Thessaloniki, Hellenic Society of Andrology (May 2024)

  • Male Age as a Factor Affecting Male Fertility – Alteration of Sperm DNA Fragmentation Levels in the Greek Population, 6th Congress of the Hellenic Society of Physicians of Assisted Reproduction & Panhellenic Association of Clinical Embryologists (April 2024)

  • Gamete Donation: Limits of Use, Questions, and Concerns, 6th Congress of the Hellenic Society of Physicians of Assisted Reproduction & Panhellenic Association of Clinical Embryologists (April 2024)

  • Number of Families Using Gamete Donation: Concerns and Limitations, 4th Conference of the Greek Society of Reproductive Medicine – Round Table: Legal and Political Aspects of Assisted Reproduction and Human Fertility (2024)

  • Male fertility preservation: a way of improving birth rates? Bonding embryologists to geneticists and fertility specialists – Assisting Nature College of Reproduction – Thessaloniki (2023)

  • The Operation of the Sperm Bank under the New Legal Framework – ΜΙΥΑ ΝΝΑ Conference (2023)

  • ORP and male infertility: Real world experience from Greece, ESHRE 39th congress -MioxSYS symposium

  • The Operation of the Sperm Bank under the New Legal Framework, 13th Panhellenic Congress of Andrology –     Athens, Hellenic Andrological Society

  • Sperm Preparation Techniques, SEMINAR by the Panhellenic Association of Bioscientists: Introduction to Clinical Embryology – Clinical and Laboratory Practices in Assisted Reproduction

  • Poster: The comparative results of 4 available glycerol only sperm cryopreservation media in a private sperm bank. Evangelini Evgeni, Dimitra Koumasi, Lazaros Karagiannidis, Lindsey VerMilyea, Alpha 13th Biennial Conference

  • Poster: P103 “Sperm static oxido-reduction potential in men with infertility and fertile men.” G Mintziori, Ε Arapogianni, D Koumasi, G Kanakis, DG Goulis, L Evgeni – 12th European Academy of Andrology Congress – Barcelona 2022

  • Poster: P102 “Decrease in sperm motility between one and three hours after ejaculation: association with the Hypo-Osmotic Swelling Test”. Ε Arapogianni, G Mintziori, DG Goulis, Ε Evgeni – 12th European Academy of Andrology Congress – Barcelona 2022

  • Poster: P071 “Correlation of reductive stress with conventional semen parameters in a Greek population cohort” Koumasi Dimitra, Kanakis Georgios, Karagiannidis Lazaros, Markogiannaki Maria Melina, Evgeni Evangelini – 12th European Academy of Andrology Congress – Barcelona 2022

  • “Sperm chromatin integrity and its impact on embryo quality and ART outcome” The future of ART – Hot topics in Reproductive Biology Procrea Lugano (April 2022)

  • “Spermiogram in the new era: Presentation of the 6th edition of the WHO manual for the examination and processing of human semen” 3rd Symposium of Assisted Reproduction Conception of Life Athens (March 2022) [GR]

  • “Sperm Morphology – is image a mirror of function?” 12th Panhellenic Andrology Congress of the Hellenic Andrology Society (June 2021). [GR]

  • “The correlation between male age and numerical and structural chromosomal anomalies – its effect on sperm DNA fragmentation” – 3rd Panhellenic Congress of Reproductive Medicine (October 2020). [GR]

  • “COVID-19 & SPERM” 1st Webinar Hellenic Andrology Society (June 2020) [GR]

  • “Seminal Oxidative Stress: A contemporary approach of male infertility evaluation”– 4th joined Congress of the Hellenic Society of Doctors in Assisted Reproduction and the Panhellenic Society of Clinical Embryologists Athens (February 2020). [GR]

  • “Making a family: How the dream comes true. Evaluation and preservation of male fertility” 1st Fertility Festival – Zappeion Athens (June 2019) [GR]

  • “Sperm Cryopreservation Banks: Specifications-Current developments” ART Clinic Athens Naval Hospital (May 2019). [GR]

  • “Semen analysis as the mirror of spermatogenesis” in the context of the 11th Panhellenic Andrology Congress of the Hellenic Andrology Society (May 2019). [GR]

  • “The effect of cryopreservation in sperm fertilizing potential” in the context of the 11th Panhellenic Andrology Congress of the Hellenic Andrology Society (May 2019). [GR]

  • “Male fertility preservation in the context of spermotoxic therapy” presentation in the Radiology Department of Attikon Hospital of Athens (April 2019). [GR]

  • “ROS: friend or foe? The role of free radicals in male (in)fertility” (invited speaker) in the context of the scientific meetings organized by the IVF Unit of IASO ‘Institute of Life’ (November 2018). [GR]

  • “Diagnostic Semen Analysis as Indicator of Male Fertility” in the context of the 14th Panhellenic Congress of Obstetrics and Gynaecology (May 2018). [GR]

  • “Sperm Function Tests: Contemporary Laboratory Approach – Clinical Applications” 3rd joined Congress of the Hellenic Society of Doctors in Assisted Reproduction and the Panhellenic Society of Clinical Embryologists Athens (February 2018). [GR]

  • “Sperm Freezing and Cryopreservation: male fertility preservation in the context of spermatotoxic therapy” in the context of the educational andrology seminars of the Hellenic Andrology Society entitled: ‘Neoplasms and Fertilty’ (February 2017). [GR]

  • “Seminology Laboratory: Reflections on result reporting” in the context of the 10th Panhellenic Andrology Congress of the Hellenic Andrology Society (March 2017). [GR]

  • “Semen Cryopreservation Banks: Basic principles of organization and function” (invited speaker) in the context of the scientific meetings organized by the IVF Unit of IASO ‘Institute of Life’ (November 2016). [GR]

  • “Basic Semen Analysis” in the context of the educational andrology seminars of the Hellenic Andrology Society entitled: ‘From the Laboratory to Clinical Practice’ (October 2016). [GR]

  • “Semen Analysis – The Laboratory Perspective” in the context of the educational andrology seminars of the Hellenic Andrology Society entitled: ‘Fertility’ (January 2016). [GR]

  • “Semen Cryopreservation” in the context of the educational andrology seminars of the Hellenic Andrology Society entitled: Assisted Reproduction Techniques in Male Infertility’ (January 2016). [GR]

  • “Applications – diagnostic value of semen analysis in the context of assisted reproduction” – 2nd joined Congress of the Hellenic Society of Doctors in Assisted Reproduction and the Panhellenic Society of Clinical Embryologists Athens (November 2015). [GR]

  • “Spermiogram – how do we interpret the new W.H.O. 2010 guidelines” – 42nd Panhellenic congress of the Hellenic Society of Endocrinology Thessaloniki (May 2015). [GR]

  • “Spermiogram” in the context of a scientific symposium entitled: “Male infertility in the era of crisis” – Military Naval Hospital Athens (June 2014). [GR]

  • “Infertility – the role of human semen in reproduction” – Athens Science Festival Technopolis (May 2014). [GR]

  • “Semen Banking: Principles and function” in the context of the professional seminars organized by the Panhellenic Association of Bioscientists and the Panhellenic Association of Clinical Embryologists (December 2012). [GR]

  • “Semen and Testicular Tissue Cryopreservation” in the context of the professional seminars organized by the Panhellenic Association of Bioscientists and the Panhellenic Association of Clinical Embryologists (June 2012). [GR]

  • “Spermiogram and Infection” in the context of the educational andrology seminars of the Hellenic Andrology Society entitled: “Genital Infections”(March 2011). [GR]

  • “The role of oxidative stress in male infertility”. Aetiology – Diagnostic evaluation – Therapeutic approach. 7th Panhellenic Congress on Free Radicals and Oxidative Stress – Spetses (June 2010). [GR]

Συνεντεύξεις και Ομιλίες

Η συμπρωτεύουσα Θεσσαλονίκη φιλοξένησε με επιτυχία την τέταρτη στάση της Πανελλαδικής Εκστρατείας «ΜΑΖΙ ΣΤΟΝ ΚΥΚΛΟ ΤΗΣ ΖΩΗΣ»

Ανακοίνωση έκδοσης του επιστημονικού συγγράμματος "Male Infertility: Management of Infertile Men in Reproductive Medicine" από τον ακαδημαϊκό οίκο Elsevier

Η Διευθύντρια της Κρυογονίας, Δρ Λίνα Α. Ευγενή, είχε τη χαρά να παρευρεθεί στην κοπή της πρωτοχρονιάτικης πίτας του Ελληνικού Συμβουλίου Τουρισμού Υγείας (ΕΛΙΤΟΥΡ) στο εστιατόριο του Μουσείου Μπενάκη